2,5-Dimethoxybenzaldehyde CAS 93-02-7

Marka lagu daro oksidized ama la dhimay 2,5-dimethoxybenzoic acid, benzonitrile ama khamriga benzyl, 2,5-dimethoxybenzaldehyde lafteedu waxay sidoo kale leedahay qiimo codsi gaar ah. Iyadoo la falcelinayo walxaha leh noocyo kala duwan oo kooxo shaqeynaya, molecules daroogada leh qaabab kala duwan iyo saameyno kala duwan ayaa la heli karaa. Cudurka Parkinson (PD) waa cudur caadi ah oo neurodegenerative ah, calaamadaha ugu muhiimsan ee bukaan-socodka waxaa ka mid ah gariir murqaha, qallafsanaanta, dhaqdhaqaaqa dhaqdhaqaaqa, joogsiga jirka iyo cilladaha dheellitirka dhaqdhaqaaqa. Horumarin dheeraad ah ayaa sidoo kale u horseedi doona aqoonsi, garasho, cillado xusuusta iyo waallida cad. Waqtigan xaadirka ah, daaweynta PD inta badan waxaa ka mid ah daaweynta daroogada, daaweynta qalliinka iyo daaweynta hidda-wadaha. Daawaynta daroogada, phenamidine waxaa lagu ogaadey inay saameyn togan ku leedahay PD, oo leh sunta hoose iyo badbaadada wanaagsan, iyo isku dhafka phenamidine wuxuu u baahan yahay isticmaalka 2,5-dimethoxybenzaldehyde sida qalab bilow ah.

Marka loo eego habka isku-dhafka ah ee lagu soo warramey suugaanta, 2,5-dimethoxybenzaldehyde waxaa inta badan lagu helaa iyada oo la falcelinayo 1,4-dimethoxybenzene oo leh wakiilka qaabeynta. Waxyaalaha qaabaynta waxaa ka mid ah (1) isku dar ah 1,1-dichloromethyl ether iyo titanium tetrachloride; (2) isku dar ah N, N-dimethylformamide iyo fosfooraska oxychloride, isku dar ah N, N-dimethylformamide iyo oxalyl chloride; (3) isku dar ah N, N-dimethylformamide iyo thionyl chloride ama isku dar ah urotropine iyo magnesium chloride. Si kastaba ha ahaatee, hababkani waxay u baahan yihiin isticmaalka qadar badan oo ah titanium tetrachloride, fosfooraska oxychloride ama thionyl chloride. Reagen-yaashani waa kuwo aan degganayn oo si fudud u burburay, iyo xaddi badan oo gaas hydrochloric acid ah ayaa la sii daayaa inta lagu jiro falcelinta, taas oo aan ahayn mid deegaanka u wanaagsan oo leh shuruudo sare oo loogu talagalay habka hawlgalka.

Hab cusub oo isku dhafan ayaa la soo jeediyay. Habkani wuxuu isticmaalaa 1,4-dimethoxybenzene iyo formaldehyde sida alaabta ceeriin, oo waxay qabataa falcelinta isku-xidhka photooxidative ee joogitaanka oksijiinta iyo kicinta hoos yimaada iftiinka buluugga ah si ay si hufan u soo saaraan 2,5-dimethoxybenzaldehyde. Habkani waxa uu u isticmaala ogsijiin ama hawo sida oksaydhiye, ma soo saaro gaas acidic ah, waana deegaan u fiican. Intaa waxaa dheer, habkani wuxuu isticmaalaa cobalt raqiis ah sida kicinta, kaas oo qiimo jaban oo ku habboon codsiga warshadaha.