Celastrol CAS 34157-83-0

CAS:34157-83-0

Qaanuunka molecular:C29H38O4

Miisaanka Molecular:450.61

EINECS:636-472-5

La mid ah:CELASTROL (SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(Fadlan wac); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

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Waa maxay Celastrol CAS 34157-83-0?

Celastrol waa mid aan lagu milmin biyaha, ku milma dimethyl sulfoxide iyo ethanol anhydrous ah. Ka soo jeeda maaddooyinka firfircoon ee ka hortagga kansarka ee dhirta sida Thunder God Vine iyo Koonfurta Maska Vine ee qoyska Celastraceae. Proteasome inhibitor wax ku ool ah, ayaa la xaqiijiyay inuu kiciyo apoptosis unugyada kansarka iyadoo la joojinayo dhaqdhaqaaqa borotiinka

Tilmaamid

Shayga	Tilmaamid
Barta karkarinta	645.7±55.0 °C (La saadaaliyay)
Cufnaanta	1.2
barta dhalaalaysa	219-230°C
pKa	4.78±0.70 (La saadaaliyay)
ugu badnaan	424nm (MeOH) ( shid)
Xaaladaha kaydinta	-20°C

Codsiga

Celastrol waxaa loo isticmaalaa go'aaminta nuxurka/aqoonsiga/tijaabada dawooyinka, iwm. Saamaynta dawooyinka: Waxay leedahay sifooyin antioxidant xoog leh, saamaynta anti-kansarka angiogenesis, iyo saamaynta rheumatoid-ka. Proteasome inhibitor wax ku ool ah, ayaa la xaqiijiyay inuu kiciyo apoptosis unugyada kansarka iyadoo la joojinayo dhaqdhaqaaqa borotiinka