Cellulose Hydroxypropyl CAS 9004-64-2
Hydroxypropyl Cellulose (HPC) CAS 9004-64-2 waa unug cellulose ah oo aan ionic ahayn oo laga sameeyay falgalka cellulose dabiiciga ah iyadoo la adeegsanayo propylene oxide ka dib marka alkaliin la sameeyo.
Hydroxypropyl Cellulose (HPC) waa polymer cellulose ether ah oo aan ionic ahayn oo laga helo wax ka beddelka kiimikada ee cellulose-ka dabiiciga ah. Iyada oo ay ugu wacan tahay soo bandhigidda kooxda hydroxypropyl (-OCH₂CH (OH) CH₃) qaab-dhismeedkeeda molecular-ka, Hydroxypropyl Cellulose waa mid biyo-milmi kara, sameeya filim iyo sameeya thermogel, cellulose-na hydroxypropyl waxaa loo isticmaalaa sidii wax lagu daro oo shaqeynaya oo ku saabsan daawada, cuntada iyo kiimikooyinka maalinlaha ah.
| SHAYGA | Heerka Caadiga ah |
| Muuqaalka | Cad ilaa huruud-cad ama kareem budo ama midab leh oo granular ah, hygroscopic ka dib qalajinta. |
| Milmida | Ku milma biyaha qabow, ethanol (96 boqolkiiba) iyo propylene glycol oo bixiya xalal colloidal ah, oo aan ku milmi karin biyaha kulul |
| Aqoonsiga AC | Waafaqsan |
| PH (25℃) | 5.0-8.0 |
| Silica | ≤0.6% |
| Haraaga shidista | ≤0.8% |
| Lumis marka la qalajiyo | ≤5.0% |
| Qiimaha TG | 130C-150℃ |
| Pb | ≤3ppm |
| Hg | ≤0.1ppm |
| AS | ≤lppm |
| Cd | ≤1ppm |
| Hydroxypropyl | 53.4-80.5% |
| Viscosity (2% Xal, 20℃) | 6.0-11.2mPa.s |
| Biraha culus | ≤10ppm |
| Cabbirka walxaha | 100% Gudub 40 shabaq |
| Khamiirka guud & caaryadaColiforms | ≤100cfu/g |
| Total aerobic Microbial Courttsl | ≤1000cfu/g |
1. Qaybta daawada (qaybta codsiga asaasiga ah, waa inay u hoggaansantaa heerarka heerka daawada, sida USP, EP, CP)
Waxyaabaha dheeraadka ah ee daawada adag ee afka laga qaato
Binder: Hydroxypropyl Cellulose HPC waxaa loo isticmaalaa habka granulation-ka ee kiniiniyada iyo kaabsulka (tusaale ahaan, granulation-ka qoyan, xal biyood oo ah 1% ilaa 5% HPC ayaa loo isticmaalaa sidii xidhmo si loo xoojiyo dareeraha iyo adkaanta granules-ka loona yareeyo dib u dhaca kala-baxa kiniinka).
Kala-baxa: Heer hoose oo ah HPC-ga beddelka ah (heerka beddelka 0.2-0.4), sababtoo ah waxa ku jira kooxaha hydroxyl ee aan la etherin, waxay leedahay sifooyin barar oo xooggan ka dib marka ay nuugto biyaha waxaana loo isticmaali karaa sidii kala-baxa kiniiniyada (qiyaasta 2% - 5%).
Maaddada dahaarka: Hydroxypropyl cellulose ee kiniiniyada. Xalka ethanol ee HPC (5% - 10%) waxaa loo isticmaalaa dahaarka filimada kiniinka si loo sameeyo filim ilaalin hufan, kaas oo qarinaya dhadhanka qadhaadhka ah ee daawada, xoojiya xasilloonida, oo aan saameyn ku yeelan kala-goynta.
Qalabka qalfoofka sii daaya ee waara: HPC oo aad u dhuuban ayaa loo isticmaali karaa sida shaxda qalfoofka ee kiniiniyada sii daaya ee waara (iyadoo la isticmaalayo qiyaas ah 20% ilaa 50%), heerka sii daynta daawadana waxaa xakameeya heerka kala dirida ee lakabka jelka HPC, taasoo gaarta sii dayn waara 12 ilaa 24 saacadood.
Waxyaabaha dheeraadka ah ee jirka lagu mariyo
Hydroxypropyl Cellulose HPC waxaa loo isticmaalaa dhibcaha indhaha, jelka iyo boomaatooyinka sida dhumuc-dheer (si loo hagaajiyo daxalka diyaarinta loona dheereeyo waqtiga joogitaanka daawada goobta lagu sameeyay) iyo xasiliye (si looga hortago in walxaha daawada ay soo daataan).
2. Hydroxypropyl cellulose ee cuntada (waa inay u hoggaansantaa heerarka heerka cuntada, sida FDA, GB 2760)
Walxaha dhumucda iyo xasiliyeyaasha
Hydroxypropyl Cellulose HPC waxaa loo isticmaalaa cabitaannada (sida cabitaannada bakteeriyada lactic acid, casiirka miraha), jalaatada, iyo macaanka si loo xoojiyo isku-dhafka badeecada, loo hagaajiyo qaab-dhismeedka (sida jilicsanaanta jalaatada), iyo looga hortago kala-soocidda ama kala-soocidda biyaha (qiyaasta: 0.1% ilaa 1.0%).
Wakiilka sameynta filimada
Hydroxypropyl Cellulose HPC waxaa loo isticmaalaa "filimka dhegdhegga la cuni karo" ee loogu talagalay miraha iyo khudaarta (miraha biyaha ee HPC waa la buufiyaa oo la qalajiyaa si loo sameeyo filim hufan), taasoo yaraynaysa khasaaraha biyaha iyo wasakhowga microbial-ka, waxayna dheereyneysaa muddada ilaalinta.
Hagaajinta dubista
Hydroxypropyl Cellulose waxaa lagu daraa rootiga iyo cajiinka keega si loo wanaajiyo dabacsanaanta cajiinka, taasoo ka dhigaysa badeecada la dhammeeyay mid jilicsan oo jilicsan, waxayna dheereyneysaa cimriga kaydinta (qiyaastu waa 0.2% ilaa 0.5%).
3. Dhinaca kiimikada maalinlaha ah iyo qurxinta
Alaabta daryeelka maqaarka
Hydroxypropyl Cellulose, oo ah qoyaan-cellulose iyo dhumuc-dhejin, ayaa loo isticmaalaa kareemada, kareemada wejiga iyo waxyaabaha ku jira si loo kordhiyo daxalka badeecadaha (kor loogu qaado dareenka maqaarka marka la isticmaalo), isla markaana samaysta filim dusha sare ee maqaarka si loo yareeyo uumiga biyaha (muddada qoyaanku waxay gaari kartaa 4 ilaa 8 saacadood).
Qurxinta
Hydroxypropyl Cellulose waxaa loo isticmaalaa aasaaska iyo mascara sidii wakiil filim sameeya iyo firdhiye, taasoo kor u qaadaysa dhegdhegga qurxinta (waxay u badan tahay inay soo baxdo), isla markaana ka dhigaysa midabka mid si siman u kala firirsan (midab deggan).
Daawada ilkaha
Hydroxypropyl Cellulose, oo ah qalab isku xidha oo dhumuc weyn, ayaa nidaamiya daxalka daawada cadayga (ka hortagga in walxaha adag ay degaan), waxay hagaajisaa "dareenka adag" inta lagu jiro cadayashada, mana aha mid xanaaq badan.
4. Goobaha kale ee warshadaha
Dahaarka iyo khad
Hydroxypropyl cellulose waxaa loo isticmaalaa sidii wakiil dhumuc iyo simitaan ah oo ku jira dahaarka biyaha ku salaysan iyo khad daabacan si looga hortago kala-soocidda midabka iyo hagaajinta simitaanka ee dahaarka (iska ilaalinta calaamadaha burushka).
Warshadaha qalabka dhismaha
Hydroxypropyl Cellulose waxaa loo isticmaalaa hoobiyaha sibidhka iyo budada putty-ka sidii wakiil biyaha celiya (si loo yareeyo uumiga biyaha xad-dhaafka ah loogana hortago dildilaaca) iyo dhumuc (si loo hagaajiyo dareeraha dhismaha).
Qalabka elektarooniga ah
HPC-ga saafiga ah waxaa loo isticmaalaa sidii resin sameynta filimka loogu talagalay iska caabbinta sawir-qaadista habka wax soo saarka jajabka semiconductor-ka (waxyaabaha wasakhda ah waa in si adag loo xakameeyaa).
1. Tilmaamo badan oo viscosity ah ayaa la heli karaa. Siddeed HPCS oo kala duwan ayaa la waafajiyaa viscosities kala duwan iyadoo loo eegayo qaybta daawada ee macaamiisha. Saamaynta codsiga ayaa ka wanaagsan.
2. Waxyaabaha ku jira isku-dhafka arsenic waa yar yihiin. Waxyaabaha ku jira arsenic ee suuqa yaallaa waa ka yar yihiin 200 PPM, waxaana ku xakamayn karnaa wax ka yar 2PPM. Ku darista daawooyinka waa mid aan waxyeello lahayn oo waxtar badan leh.
3. Waxaan habeyn karnaa HPC-ga nuugista sare leh. Tilmaamaha nuugista sare leh waxaa loo isticmaali karaa agabka loogu talagalay diyaarinta sii-deynta joogtada ah iyo sii-deynta la xakameeyey. Iyadoo la hagaajinayo nuugista, heerka sii-deynta daawada si sax ah ayaa loo xakameyn karaa, taasoo kordhinaysa waxtarka wax soo saarka ee badeecada la dhammeeyey.
Waxyaabaha ku jira hydroxypropyl cellulose waa cellulose dabiici ah oo wax laga beddelay, kaas oo laga sameeyay cellulose dabiici ah iyada oo loo marayo wax ka beddelka kiimikada mana ku jiraan qaybo badan oo isku dhafan. Hydroxypropyl cellulose ammaan ah ayaa loo aqoonsaday caalami ahaan. Haddii aad rabto inaad iibsato hydroxypropyl cellulose, w waxay ku siin doontaa qiimo wanaagsan. 25kg/durbaan.
L-HPC CAS 9004-64-2 Hydroxypropyl Cellulose Bixiyeyaasha
L-HPC CAS 9004-64-2 Hydroxypropyl Cellulose Bixiyeyaasha
