SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

isku macno ah:

5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;TokyoViolet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4Kimikada Buug-dione;SHIKONIN(AS);Shikonin,froMArnebiasp.;(-)-ShikoninShiinaha;Shikonine;Shikonin5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Magaca Summada: Unilong
Meesha Asalka ah: Shandong, Shiinaha
Daahirnimo: 99%

Magaca badeecada: SHIKONIN

Xirmooyinka: 25kgs/durbaan

Gaarsiinta: Isla markiiba

MF:C16H16O5

MW:288.3

Farriintaada ka tag

Faahfaahinta Badeecada

Soo dejiso

Calaamadaha Alaabta

Waa maxaySHIKONIN

Kilrasta irbadda guduudan-bunni, dhibic dhalaalaysa 147℃, wareegga indhaha αD20=+135°(benzene). Ku milma phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, saliidaha xayawaanka iyo khudaarta iyo xalalka biyaha alkaline, oo aan ku milmi karin biyaha. Midabku wuu isbeddelaa marka qiimaha Ph uu noqdo casaan, iyadoo qiimaha Ph uu yahay 4-6 uu yahay casaan, qiimaha Ph uu yahay 8 uu yahay guduud, iyo qiimaha Ph uu yahay 10-12 oo ah buluug. Iska caabbinta iftiinka oo wanaagsan, iska caabbinta kulaylka iyo iska caabbinta oksaydhka, oo aan degganayn ilaa la yareeyo qiyaasta, iyo guduud madow haddii ay dhacdo ion bir ah. Waxay leedahay saameyn bakteeriyada dila ah oo gaar ah.

QeexitaankaSHIKONIN

CAS	517-89-5
Magacyo Kale	Shikonine
Muuqaalka	budo guduudan
Daahirnimo	99%
Midab	guduudan
Kaydinta	Kaydinta Qabow ee Qalalan
Xirmo	25kg/bac
Codsiga	Cunto

CodsigaSHIKONIN

(1) Saamaynta Hoos u dhaca sonkorta dhiigga Soosaarka caleenta comfrey iyo polysaccharide (A, B, C) ee comfrey waxay leeyihiin saameyn muuqata oo hoos u dhac ku yimaada sonkorta dhiigga.

(2) Saamaynta bakteeriyada Lithospermum waxay leedahay saameyn xakameyn ah oo ku saabsan fayraska Jingke 68-1 in vitro, waxayna leedahay saameyn xakameyn ah Staphylococcus aureus. Saamaynta fayraska ka hortagga parainfluenza ee levoshikonin waxaa lagu bartay falgalka hemagglutination iyo habka cytopathological. Natiijooyinka waxay muujiyeen inay leedahay sun yar oo ku jirta heerka fiirsashada ee loo isticmaalay tijaabada, waxayna leedahay firfircooni fayras ka hortagga hargabka ee in vitro iyo dil toos ah oo fayraska parainfluenza ah.

(3) Saamaynta xinjirowga dhiigga: Cirbadaha gudaha caloosha ee qaybaha shikonin (shikonin, acetylshikonin) ma saameeyaan waqtiga xinjirowga dhiigga, laakiin waxay ka hortagi kartaa saameynta xinjirowga dhiigga ee heparin.

(4) Saamaynta ka hortagga burooyinka Soosaarka Comfrey wuxuu leeyahay saameyn xakameyn ah oo ku saabsan marxaladda dambe (marxaladda G2) ee sameynta DNA-da ee unugyada Hela.

(5) Saamaynta ka hortagga burooyinka Shikonin waxay joojisaa faafitaanka, waxay kor u qaadaa apoptosis waxayna kicisaa joojinta wareegga unugyada ee khadadka unugyada daawada u adkaysta ee choriocarcinoma ee aadanaha (JAR/MTX) in vitro. Tijaabooyinku waxay muujinayaan in fiirsashada shikonin ay korodho marka la qaato qiyaasta. Iyo kordhinta waqtiga ficilka, heerka joojinta ee koritaanka unugyada daawada u adkaysta choriocarcinoma ayaa sidoo kale si weyn u kordhay.

(6) Saamaynta dheecaanka hoormoonka Saamaynta shikonin ee shaqada dhidibka hypothalamic-pituitary-gonadal ee jiirka dheddigga ah ee qaangaaraya ayaa muujisay in heerarka hoormoonka serum-ka ee kooxda shikonin ay si weyn uga hooseeyaan kuwa kooxda xakamaynta taban, mana jirin farqi weyn marka la barbar dhigo kooxda xakamaynta togan. way ka duwan tahay. Waxay muujinaysaa in shikonin uu joojin karo shaqada dhidibka hypothalamic-pituitary-gonadal ee jiirka.

(7) Saamaynta Ka-hortagga oksaydheynta Qaar ka mid ah cilmi-baarayaashu waxay cabbireen awoodda xoqidda shikonin ilaa xagjirka superoxide (O2-) iyo 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), iyo saameynta ay ku leedahay β-- Joojinta nidaamka ka-hortagga oksaydheynta carotene/linoleic acid. Natiijooyinka waxay muujiyeen in shikonin uu leeyahay awood xoqid oo xooggan oo ku wajahan DPPH iyo O2-, wuxuuna lahaa saameyn xakameyn oo cad oo ku saabsan nidaamka oksaydheynta otomaatiga ah ee β-carotene/linoleic acid. Awood antioxidant oo xooggan.